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Investigations on the replacement of the mouse neutralisation test for proving vaccine batches of Clostridium (C.) perfringens toxoid vaccines were performed since several years. Production of platelet-derived growth factorlike protein(s) by a human carcinoma cell line. The initial fouling characteristics of aerobic submerged membrane bioreactors (MBRs) were analysed under different flux conditions. It is possible that this syndrome may be due to a muscle abnormality.
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